Impact of curcumin on fatty acid metabolism

نویسندگان

چکیده

Free fatty acids (FFAs) and acid synthesis (FAS) activity have significantly contributed to disease states such as insulin resistance, obesity, type 2 diabetes, myocardial infarction, blood pressure, several types of cancer. Currently, treatment options are available for patients with these conditions. Due safety concerns, adverse effects, limited efficacy, low tolerability associated many medications, the identification novel agents less toxicity a more favorable outcome is warranted. Curcumin phenolic compound derived from turmeric plant various biological activities, including anticarcinogenic, antioxidant, antiinflammatory, hypolipidemic properties. PubMed, Scopus, Web Science were searched up February 2020 studies that demonstrated efficacy mechanisms curcumin action on FFAs, FAS, β-oxidation activity, well desaturation system. Most evidence in-vivo in-vitro demonstrate possesses regulatory properties FFAs levels through its effects FAS system, which could improve other FFAs-related disorders. The present study provides review existing in-vitro, in-vivo, clinical effect β-oxidation,

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ژورنال

عنوان ژورنال: Phytotherapy Research

سال: 2021

ISSN: ['1099-1573', '0951-418X']

DOI: https://doi.org/10.1002/ptr.7105